Areni-1 is an ancient winery that was discovered in 2007 in a cave near the village of Areni in Armenia. It is the oldest known winery in the world, dating back to around 4000 BC. It shows that wine production was already a sophisticated and established practice in the region, and that the grape varieties used were domesticated forms of Vitis vinifera. It consists of a grape press, fermentation vats, storage jars, and drinking cups, as well as grape seeds, skins, and vines. The wine was probably used for ceremonial purposes, as the cave also contained burial sites. In fact, three skulls were found. They are among the oldest human remains discovered in Armenia, dating back to the late Chalcolithic or early Bronze Age, around 4000 BC. They belong to three individuals, two adults and one child, who were buried in separate niches inside the cave. The skulls were intentionally separated from the rest of the skeletons, which were not found in the cave. They were covered with clay pots, which may have had symbolic or ritual significance, and they are well-preserved, and one of them still contains a piece of brain tissue, which is the oldest known human brain in the world.